The program includes eight men's sports: baseball, basketball, cross country, football, golf, soccer, track and field, and wrestling.

The women's program has ten sports: basketball, cross country, golf, soccer, softball, swimming and diving, tennis, track and field, and volleyball.

The ThunderWolves won the 2014 NCAA Division II Football National Championship, its first in football program history, by blanking previously undefeated Minnesota State University, Mankato 13–0.

[3][4] In 1984, the school ended its football and baseball programs due to budget cuts.

CSU Pueblo announced further restoration of athletic programs under new president Lesley Di Mare.