On 9 December 2009, he made his first official appearance with the first team, playing 90 minutes against Rangers in the UEFA Champions League in a 1–0 group stage home win.

[8] He was regularly used by the second-tier team during his spell, making his official debut on 11 September in a 5–1 home victory over FC Barcelona B and finding the net in the game.

[9] On 5 July 2011, Cala signed a one-year loan deal with AEK Athens FC, where he reunited with former Sevilla boss – main squad and reserves – Manolo Jiménez, as well as teammate José Carlos.

[12] Cala was recalled by Sevilla in late January 2012, as a replacement for Juventus FC-bound Martín Cáceres; AEK received €60,000 in compensation.

[16] He made his debut for his new team eight days later, playing the full 90 minutes in a 2–1 home loss against Wigan Athletic in the round of 16 of the FA Cup.

[26] On 6 August 2016, Cala signed a season-long loan deal with FC Anzhi Makhachkala with an option of making the move permanent at the end of it.

[35][36] On 4 April 2021, shortly after having opened the scoring at the Estadio Ramón de Carranza, Cala allegedly directed a racial slur at Mouctar Diakhaby, to which the entire Valencia CF squad responded by leaving the pitch in support of their teammate.

After being informed by the referee that they would forfeit the game if it was not completed, they later returned to resume the match with the exception of Diakhaby, who urged them to play on without him and was replaced by Hugo Guillamón; Cádiz eventually won 2–1, with the winner being scored by Marcos Mauro, who had come on for Cala at half-time.

[37][38][39] In a press conference held two days later, Cala strongly denied using any racist language towards Diakhaby, claiming he had simply asked him to "leave me in peace" and that the latter had misheard what the former said as a racial slur.