During this time, cities in the district included Los Banos, Madera, Merced, and most of Fresno.

Cities in the new 16th district include Pacifica, Half Moon Bay, Atherton, Palo Alto, Saratoga, Campbell, Woodside, and Los Gatos, along with the south-central and southwestern parts of San Jose.

[5] As of the 2020 redistricting, California's 16th congressional district is located in the San Francisco Bay Area.

The 16th and 19th are partitioned by Old Santa Cruz Highway, Aldercroft Hts Rd, Weaver Rd, Soda Springs Rd, Love Harris Rd, Pheasant Creek, Guadalupe Creek, Guadalupe Mines Rd, Oak Canyon Dr, Coleman Rd, Meridian Ave, Highway G8, Guadalupe River, W Capitol Expressway, Senter Rd, Sylvandale Ave, Yerba Buena Rd, Silver Creek Rd, and E Capitol Expressway.

The 16th and 17th are partitioned by Stevens Creek Blvd, Santana Row, Olsen Dr, S Winchester Blvd, Williams Rd, Eden Ave, Lexington Dr, Valley Forge Way, Gleason Ave, Moreland Way, Payne Ave, Saratoga Ave, Doyle Rd, Highway G2, Royal Ann Dr, Wisteria Way, Rainbow Dr, Highway 85, S De Anza Blvd, Prospect Rd, Fremont Older Open Space, Permanente Creek, Highway 280, N Foothill Blvd, Homestead Rd, Stevens Creek, W EL Camino Real, Magritte Way, Highway G6, Highway 101, and Enterprise Way.