[4] Immediately after, SR 905 turns south to its final interchange at Siempre Viva Road before the route ends at the Otay Mesa Port of Entry,[5] which traffic of large trucks must use to cross the border.

[11] A paved road connected San Ysidro to Brown Field and the easternmost ranches in the Otay Mesa area by 1935.

[12] Discussions were held between San Diego County and National City over the maintenance of the road in 1950, since it was used by trucks travelling to the landfill.

[16] The California Highway Commission endorsed the routing for SR 75 in 1965 along Otay Mesa Road, away from future residential developments.

[17] There were plans as early as 1970 to have a highway heading southwest to a new border crossing that would bypass the Tijuana area.

[21] Later, the Comprehensive Planning Organization (CPO), the local association of municipal governments, recommended using $4 million of federal funding for the construction of SR 75.

[25] Following this, Representative Lionel Van Deerlin attempted to accelerate the construction of the crossing, even though there was no funding for the highway.

[31] In late 1977, the CPO made plans to push for adding SR 117 to the Interstate Highway System, to obtain additional federal funding.

[32] By 1979, both San Diego city and county had allocated $6 million to construct a temporary way to access the border crossing along Otay Mesa and Harvest Roads.

[5] Efforts were underway in 1997 to secure federal funding for the highway and other infrastructure near the Mexican border, largely supported by Senator Barbara Boxer and Representative Bob Filner,[39] and Representative Bud Schuster, the chairman of the House Transportation and Infrastructure Committee, visited the region before giving informal approval to the proposal.

[6] In 1999, Governor Gray Davis approved allocating $27 million in federal funding to complete the freeway.

Before, it had 50 percent more traffic than it was designed to handle;[43] it was considered by the San Diego Union-Tribune as "California's busiest trade route with Mexico."

[44] The next year, the California Transportation Commission allocated $25 million of state funding towards completing the freeway.

[48] The interchange with I-805 began to be upgraded in April 2011,[50] and the construction, which used $20 million in federal funding,[51] finished in February 2012.

[55] SR 11 is planned to be a toll facility that will serve a new border crossing east of Otay Mesa.