It is planned to be extended from Enrico Fermi Drive to the proposed U.S.–Mexico border crossing at Otay Mesa East.

[1] On that segment, plans were to construct two interchanges at Enrico Fermi Drive and Siempre Viva Road as the proposed route curves to the southeast before reaching the border crossing.

[2] Four years later, several parties, including District 11 of the California Department of Transportation (Caltrans), the City and County of San Diego, the San Diego Association of Governments, and Tijuana were signatories to a Letter of Intent to build the border crossing.

By the following year, several alternatives were considered to construct some or even none of the interchanges or remove the proposed toll on the route.

The California Transportation Commission endorsed the project in January 2012,[5] and approved the proposed freeway route that December.

[1][16][17] The second phase, connecting to the future Otay Mesa East Port of Entry, began construction in August 2019 and was scheduled to be completed in late 2021.