Founded by Timber Pizza co-founders Andrew Dana and Daniela Moreira, its first location opened in Park View, Washington, D.C., in October 2018.

[1] Washington native Dana had partnered with Chris Brady and Daniela Moreira to launch Timber Pizza's first brick and mortar location in Petworth in 2016.

[6] Growth slowed only slightly during the COVID-19 pandemic; after a two-week closure, Call Your Mother reopened with a focus on pickup and delivery and did not lay off any employees.

In January 2021, Call Your Mother's Georgetown location became the first restaurant visited by newly inaugurated President Joe Biden when his motorcade passed by on his way back from church.

[7] Zients, then serving as White House coronavirus response coordinator, had divested his stake in the restaurant prior to joining the Biden administration.