It is native to the Bahamas where it is found at a depth of 31.5-44.2 m. It was first described in 1814 by Jean-Baptiste Lamarck.

The vent at the top is up to 6.5 cm in diameter and has a thin, transparent collar.

They are typically pink or light blue, but may be other colors including tan, peach or yellow and show a predominantly light blue iridescence.

[2] Since Callyspongia plicifera do not produce chemical deterrents to fish grazing, they heal and grow at a faster rate following fish grazing than other sponge species in the Caribbean.

The Callyspongia plicifera has an average healing rate of 8% area regeneration per day following fish grazing.