Cambodia competed at the 2020 Summer Olympics in Tokyo.

Originally scheduled to take place from 24 July to 9 August 2020, the Games were postponed to 23 July to 8 August 2021, due to the COVID-19 pandemic.

[1] This was the nation's seventh consecutive appearance at the Summer Olympics in the post-Soviet era.

Cambodia received universality slots from IAAF to send one athlete to the Olympics.

[3] Cambodia received a universality invitation from FINA to send two top-ranked swimmers (one per gender) in their respective individual events to the Olympics, based on the FINA Points System of June 28, 2021.