Cambridge-Isanti High School is a four-year public high school located in Cambridge, Minnesota, United States.

The page for this school on the web site of the Minnesota State High School League (MSHSL) shows a present enrollment of 1377 students in grades nine through twelve.

Cambridge-Isanti competes in the Mississippi 8 Conference, consisting of either other central Minnesota schools.

Prior to the formation of the Mississippi 8 Conference Cambridge-Isanti competed in the North Suburban Conference

This Minnesota school-related article is a stub.