The campus is 24 miles southeast of Moline, Illinois and serves a mixed village and rural residential community.

The school is near the Quad Cities and is part of the Davenport-Moline-Rock Island, IA-IL metropolitan statistical area.

Many Illinois school districts see a decrease in percentile as grade level increases.

[5] In 2009, the Cambridge Junior-Senior High School faculty was 48 teachers, averaging 13.8 years of experience, and of whom 31% held an advanced degree.

A cooperative partnerships with neighboring AlWood High School was recently formed to provide opportunities despite low enrollment numbers for several athletics and activities.