Cambridge Springs is a borough with home rule status in Crawford County, Pennsylvania, United States.

Also listed on the National Register of Historic Places are the Cambridge Springs Bridge and Amos Kelly House.

[10] In 1904, the Rider Hotel in Cambridge Springs was the site of a famous chess tournament won by Frank Marshall ahead of World Champion Emanuel Lasker and fourteen other players.

A variation of the Queen's Gambit Declined opening played several times there is today known as the Cambridge Springs Defense (1.d4 d5 2.c4 e6 3.Nc3 Nf6 4.Bg5 Nbd7 5.e3 c6 6.Nf3 Qa5 in algebraic notation).

In 1912, United States President William Howard Taft traveled to Cambridge Springs for the dedication.

The site of the college is now occupied by the State Correctional Institution – Cambridge Springs, a minimum-security prison.

According to the United States Census Bureau, the borough has a total area of 0.872 square miles (2.26 km2), all land.

[6] French Creek, a tributary of the Allegheny River, flows through the northern part of Cambridge Springs.