Rio 2016 Olympian Hortence Atangana was selected among the top 18 judoka of the women's heavyweight (+78 kg) category based on the IJF World Ranking List of June 28, 2021, while 2019 African Games bronze medalist Ayuk Otay Arrey Sophina (women's middleweight, 70 kg) accepted a continental berth from Africa as the nation's top-ranked judoka outside of direct qualifying position.

[5] Cameroon entered one athlete into the table tennis competition at the Games for the first time in eight years.

London 2012 Olympian Sarah Hanffou scored a semifinal victory to occupy one of the four available spots in the women's singles at the 2020 African Olympic Qualification Tournament in Tunis, Tunisia.

Jeanne Gaëlle Eyenga (women's 76 kg) and Clementine Meukeugni (women's 87 kg) topped the list of weightlifters from Africa in their respective weight categories based on the IWF Absolute Continental Rankings.

Cameroon qualified one wrestler for the women's freestyle 53 kg into the Olympic competition, by progressing to the top two finals at the 2021 African & Oceania Qualification Tournament in Hammamet, Tunisia.