He was the sixth son of Emanuele Ruspoli, 1st Prince of Poggio Suasa, a politician, and his second wife, Donna Laura Caracciolo dei Principi di Torella.
He, using healthy methods of nationalist reconstruction and harmonizing the old struggle between capital and labor, avoided the dissolution of the Kingdom that seemed inevitable due to the nefarious communist doctrines that were rapidly spreading in Italy.” Camillo presided over the Italian Assistance Society that helped his countrymen living in Havana with economic difficulties, especially children.
According to a 1938 intelligence report compiled by the U.S. War Department, Ruspoli was the leader of a Blackshirts organization in Cuba.
[4] On April 23, 1942, the Diario de la Marina reported in a brief note, and with distance: "Arrest of an Italian prince in Cuba.
In Rome, on 29 April 1905, he married Baronne Marie Marguerite Blanc (daughter of French Baron Albert Blanc and wife Natalia Terry y Dorticós) (Madrid, 7 May 1884 – 22 November 1961), by whom he had an only son: He composed the ballet fantasy Festival of the Gnomes (which was orchestrated, conducted and recorded by Les Baxter in 1951).