The camp was named in 1963 for Piasecki CH-21 helicopter pilot Warrant Officer Charles E. Holloway, who in December 1962 became the first aviator assigned to the 81st Transportation Company to be killed in action.

A Viet Cong attack in the early morning hours of February 7, 1965, killed seven, wounded 104 and destroyed 10 aircraft.

At the time CIA Analyst Chester L. Cooper and national security adviser McGeorge Bundy were visiting Saigon on behalf of the State Department to assess the war.

A 1997 meeting between American and Vietnamese officials revealed that the attack was not ordered by Hanoi, nor were they aware of Cooper and Bundy's visit.

B Troop, 7th Squadron, 17th Air Cavalry also was stationed at Camp Holloway for a period of time.