The CPS is governed by an elected Board of Directors representing each province and territory.

The organization is a partner of CANImmunize, a vaccine passport application developed by the Canadian Public Health Association at the Ottawa Hospital Research Institute with funding from the Public Health Agency of Canada.

[1][2] The CPS administers the Canadian Immunization Monitoring Program, Active (IMPACT), a national surveillance system for vaccine-preventable diseases and vaccine adverse events in 12 pediatric tertiary care centers across Canada.

[3] IMPACT is funded by the Centre for Immunization and Respiratory Infectious Diseases at the Public Health Agency of Canada, with additional funding for surveillance for rotavirus and invasive meningococcal disease provided by GlaxoSmithKline, Merck, Novartis and Pfizer.

Funded by a $726,704 grant from the Public Health Agency of Canada's Immunization Partnership Fund, the CPS organized a workshop and online education module on vaccine hesitancy to increase uptake of COVID-19 vaccines.