Clavispora lusitaniae

[2] Clavispora lusitaniae was initially described as a rare cause of fungemia, with fewer than 30 cases reported between 1979 and 1990.

However, there has been a marked increase in the number of recognized cases of candidemia due to this organism in the last two decades.[timeframe?]

Bone marrow transplantation and high-dose cytoreductive chemotherapy have both been identified as risk factors for infections with this organism.

A study found that C. lusitaniae was responsible for 19% of all breakthrough fungemia infections in cancer patients between 1998 and 2013.

[4] Some investigators have theorized that the widespread use of Amphotericin B empiric antifungal therapy selects for infections with Candida lusitaniae.

Scanning electron microscopy (SEM) images of C. lusitaniae on filament-inducing media. Cells grown on V8 (pH = 7) media for 7 days at 37 °C were processed for SEM, and imaged (see Materials and Methods). Scale bars for upper panel (1000x) and lower panel (5000x) images represent 10 μm and 2 μm, respectively. WT (ATCC42720), cnb1 mutant (YC198), and crz1 mutant (YC187)