Canusio Lake is a freshwater body in the northeastern part of Senneterre in the La Vallée-de-l'Or Regional County Municipality (RCM), in the administrative region of Abitibi-Témiscamingue, in the province of Quebec, in Canada.

Canusio Lake is located in the township of Noiseux, Logan and Cherrier.

The hydrographic slope of Canusio Lake is accessible via a forest road (North-South direction) on the east side of the Saint-Cyr River Valley; in addition, another forest road (East-West direction) serves the South of the Mégiscane River.

The surface of Canusio Lake is usually frozen from early November to mid-May, however, safe ice circulation is generally from mid-November to mid-April.

The toponym "Lac Canusio" was formalized on December 5, 1968, by the Commission de toponymie du Québec, when it was created.