Capolona is a small town and comune in Tuscany, central Italy, on the right bank of the River Arno.

In 943, a deed of confirmation mentions Campus Leonis as being the property of a Bernardo, a noble of Arezzo.

The core of Capolona grew around the Abbey of San Gennaro [it] in Campo Leonis.

These were in turn passed to the dominion of the Tarlati di Pietramala, in 1384, after the Arezzo territories surrendered to Firenze, becoming part of the Fiorentino Republic.

In 1527, Capolona was devastated by the army of Carlo di Borbone, General of the Emperor Carlos V. The Commune of Capolona was formed in 1845 when the hamlets of Lorenzano and Baciano were combined with several areas which had been part of the municipality of Talla.