[67] Murray turned professional in April and was given a wild card entry to a clay-court tournament in Barcelona, the Open SEAT, where he lost in three sets to Jan Hernych.

[107] At Cincinnati, Murray became only one of two players, alongside Rafael Nadal, to defeat Roger Federer in 2006, breaking the Swiss star's 55 match winning streak on hard courts.

[109][110] In the final two Masters events in Madrid and Paris, Murray exited both tournaments at the last-16 stage ending his season, with losses to Novak Djokovic and Dominik Hrbatý.

[191] At Wimbledon, Murray set the then record for the latest finish at the championships when he completed a four-set victory over Marcos Baghdatis at 23:02 BST (surpassed by one minute by the 2018 men's singles semi-finals).

[195] In the mixed doubles, Murray and Laura Robson lost in the final to the Belarusian top seeds (Victoria Azarenka and Max Mirnyi) in three sets, gaining a silver medal.

[224] The Great Britain Davis Cup team played their World Group Play-off tie on clay against Croatia, where Murray beat 16-year-old Borna Ćorić in straight sets.

[245] He made it to the quarter-finals of the 2014 US Open, losing to Novak Djokovic, after earning his first top ten win of the year in the previous round against Jo Wilfried Tsonga.

[257] He lost his final group match against Federer in straight sets and only won one game against him, marking his worst defeat since losing to Djokovic in the 2007 Miami Masters, eliminating him from the tournament.

[265][266] At Davis Cup World Group in Glasgow against the United States he won both his matches against Donald Young and John Isner, allowing Great Britain to progress to the quarter-finals 3–2.

[277] To start his grass court campaign, Murray went on to win a record-tying fourth Queen's Club title, defeating the big serving Kevin Anderson in straight sets in the final.

[284] Facing Australia in the semi-finals of the Davis Cup World Group in Glasgow, Murray won both his singles rubbers in straight sets, against Thanasi Kokkinakis and Bernard Tomic.

[285] He and his brother Jamie won in five sets against Sam Groth and Lleyton Hewitt, the results guiding Great Britain to the Davis Cup final for the first time since 1978 with a 3–2 win over Australia.

After a three set win over Richard Gasquet, he joined Novak Djokovic, Roger Federer and Rafael Nadal as the only players to reach the semi-finals (or better) at all nine of the ATP World Tour Masters 1000 tournaments, and also ensured that he compiled his best match record in a single season.

At Rio Olympic Games he became the first player, male or female, to win two consecutive gold medals in the tennis singles events by beating Juan Martín del Potro in the final, which lasted over four hours.

1[311] and in doing so, became the first player to win a Grand Slam, the ATP World Tour Finals, the men's singles at the Olympic Games and a Masters 1000 title in the same calendar year.

[316] At Dubai he won his only tournament of the year, beating Fernando Verdasco in straight sets,[317] despite almost losing in the quarter-finals to Philipp Kohlschreiber where Murray had to save seven match points.

[325] As the five-time champion at Queens, Murray pledged his prize money to the victims of the Grenfell Tower fire,[326] however he was defeated in straight sets by Jordan Thompson in the first round.

[336] Later that month, Murray said he was making progress after several days of playing at the Mouratoglou Tennis Academy in Nice after posting pictures of himself practising against Aidan McHugh, a British junior player, on Instagram.

[345] At Washington, a three-set victory over Marius Copil in the third round lasted until just past 3:00 AM local time; Murray wept after the conclusion of the match, overcome with emotion.

[351] Murray had been due to play at the China Open the following week, but, after suffering a slight ankle problem, he decided to end his season early to ensure he would be fit for the following year.

[352][353] At Brisbane[354] he won his first round match against James Duckworth in straight sets but admitted post-match that he did not know how long he would be able to play top-class tennis.

[356] On 11 January, at a press conference just before the 2019 Australian Open, an emotional Murray announced that he could possibly retire from professional tennis due to struggling physically for a "long time", particularly with his hip injury.

[357] Active and retired tennis players, including Juan Martín del Potro, Kyle Edmund, Billie Jean King and the other members of the 'Big Four' paid tribute to Murray upon his announcement.

At its conclusion, a video montage of tributes featuring other top players Roger Federer, Novak Djokovic, Sloane Stephens and Caroline Wozniacki played in deference to his impending retirement.

"[364] On 7 March, Murray stated in an interview that he was now free of pain in his hip as a result of the surgery and may return to playing competitive tennis, but that he would not rush his comeback.

[367] They beat top seeds Juan Sebastián Cabal and Robert Farah in straight sets and defending champions John Peers and Henri Kontinen in the semi-finals.

[390] Having withdrawn from singles due to quadriceps strain, at Olympic men's doubles[391] Murray and Joe Salisbury reached the quarter-finals beating Nicolas Mahut and Pierre-Hugues Herbert and Kevin Krawietz and Tim Pütz before losing to Marin Čilić and Ivan Dodig.

[442] He opted against having surgery and returned to action in May at an ATP Challenger event in Bordeaux, France, where he lost his second-round match to Gregoire Barrere in straight sets.

"[477][478] His strengths included groundstrokes with low error rate, the ability to anticipate and react, and his transition from defence to offence with speed, which enabled him to hit winners from defensive positions.

Murray's coach has changed through the years: Leon Smith (1998–2004), Pato Álvarez (2003–2005), Mark Petchey (2005–2006), Brad Gilbert (2006–2007), Miles Maclagan (2007–2010), Àlex Corretja (2010–2011), Ivan Lendl (2011–2014, 2016–2017, 2022–2023), Amélie Mauresmo (2014–2016), Jonas Björkman (2015),[502] Jamie Delgado (2016–2021).