After completing an apprenticeship as a merchant, he was introduced to painting by Friedrich Carl Gröger and Heinrich Jacob Aldenrath, and Christoph Wilhelm Wohlien with whom he remained friends all his life.
[3] From 1839 to 1847 Eybe studied at the Düsseldorf Royal Arts Academy under Karl Ferdinand Sohn and later, Friedrich Wilhelm von Schadow.
Under Schadow's influence he produced paintings on religious themes, such as Hagar and Ishmael in the Desert (1845),[3] or Caritas (1847) which was acquired by the Hamburger Kunsthalle.
After study, in 1848 he became a painter at Hamburg and earned his living for a time with sculpture and portrait lithographs.
Portraits of Eybe, the pencil drawing by Christian Eduard Böttcher, and an oil by Ludwig Knaus from 1850, are kept at the Malkasten-Haus headquarters of Malkasten artists' association in Düsseldorf.