His prolific output in Denmark consisted mainly of portraits of royalty and the nobility, but included also genre paintings in the Dutch style.
He was reputed to be a competent portraitist, and is reported to have painted a large family picture for the widow Countess Lewenhaupt.
During these years in Skåne he also produced portraits, although it is not evident from the quality of his work that he ever received professional instruction at this point in his career.
He brought with him to Denmark a letter of introduction from Charlotte Amélie Dorothée Desmarez, governess at the Ramel residence and his future wife, to her brother-in-law C.G.
He started working as drawing teacher at the Academy on 4 April 1741, teaching the sons of Danish nobility, the royal pages and cadets.
His duties soon expanded at the Academy; when on 28 June 1745 he became supervisor of drawing instruction, and began making portraits for King Christian VI.
In the years 1745-1747 he began to introduce rococo into his artwork, as seen in his portraits of Countess Louise Sophie of Danneskiold-Samsøe and Adam Gottlob Moltke.
Eigtved was removed from the Director's position a few days later, and the directorship went to a Frenchman, Jacques Francis Joseph Saly.
During the early years of the Academy most of the artists and architects who served in leading positions, both managerial and educational, were not Danish.
Around 1757, neoclassicism began to replace rococo as the popular style, and his works became more romantic and dramatic with focus on shadow and light effects, and with more attention paid to depicting the models.
Around 1760 he made portraits of Adam Gottlob Moltke, his wife, and Anna Margrethe Juel which foreshadowed the arrival of Louis XVI style to Denmark.
On 10 September, he was ordered by Hereditary Prince Frederick to travel within two days to Schleswig to paint a life-size portrait of the King's sister Louise, her husband Carl Count of Hesse-Kassel and their children.
Als had been one of Pilo's best students, and had traveled to Rome and Paris, bringing back a strongly Italian-inspired painting style that became the rage.
Pilo left Denmark on 10 or 11 October and arrived in Stockholm in November, after having visited the Ramel family in Skåne.