[1] Mannich attended high school in Weimar and later on in Berlin where he left before graduating, taking an internship at a pharmacy instead.
Mannich became an extraordinary professor for Pharmaceutical Chemistry in Göttingen from 1911 to 1917, and went to Frankfurt in 1920.
Mannich also developed a method for the determination of morphine content in opium, which allowed for effective dosing without having to use complex physiological individual tests.
Mannich advanced the field of applied pharmacy with his development of various testing and detection methods.
These include polarimetry of starch in order to detect boric acid in food or the amount of ethanol in alcoholic beverages.