Carlos Humberto Perette (December 12, 1915 – June 18, 1992) was an Argentine Radical Civic Union politician and lawyer.

In 1952 Perette was elected as a national deputy and headed the greatly reduced UCR bloc towards the end of the second term of President Juan Domingo Perón.

To Perette is attributed the Pueblo ('People') tag of the party, meant to differentiate from the opposing ideas of Arturo Frondizi.

In the subsequently annulled elections of 18 March 1962 Perette was decisively beaten for the governorship of his province by the UCRI ('Intransigent Radical') candidate.

Following the fall of the military government, Perette stood as the running mate of Fernando De La Rua on the National Line slate in the internal selections for the 1983 Presidential elections, but they eventually withdrew their candidacy.