[16] After his junior year, Division I coaches were lined up to recruit Anthony to a school on the East Coast, which included North Carolina and Syracuse.

[17] In contrast to contemporary prep-to-pro players like Kevin Garnett, Jermaine O'Neal, Kobe Bryant, Tracy McGrady or Amar'e Stoudemire, he decided to declare early and announce that he would attend Syracuse University before his senior year.

As Anthony's grades dropped under a C average and his scores on the ACT were below acceptable standards, he knew that he needed to improve in the classroom to qualify academically for Syracuse.

During the summer of 2001, Anthony led an AAU Baltimore Select team to the Final Four of the Adidas Big Time Tournament in Las Vegas, Nevada.

[16] Anthony attracted attention from the NBA by averaging 25.2 points a game in the tournament, which was also attended by Amar'e Stoudemire (who was already being touted as a future lottery pick).

[19] He averaged 21.7 points, 8.1 rebounds and 4.0 assists during his senior year at Oak Hill[22] and named a USA Today All-USA First Team and a Parade First-Team All-American.

[16] Due to his struggles with the ACT, his family and friends wondered whether Anthony would forget about his college plans to attend Syracuse and move on to the NBA.

[30] Anthony said that he originally planned to stay at Syracuse for two to three seasons, but having already accomplished everything he set out to do, he chose to abandon his collegiate career (with Boeheim's blessing) and declared himself eligible for the 2003 NBA draft.

On November 23, 2005, with the Nuggets facing the two-time defending Eastern Conference Champion Detroit Pistons, Anthony hauled down his 1,000th career rebound.

[72] However, with Yao Ming and Carlos Boozer out with injuries, NBA commissioner David Stern chose Anthony as a replacement (along with Josh Howard).

Anthony finished the season as the league's second leading scorer behind Bryant, with an average of 28.9 points,[78] while adding 6.0 rebounds, 3.8 assists and 1.2 steals per game.

Sources reported that Anthony's preferred destination was the New York Knicks, with other teams such as the New Jersey Nets, Houston Rockets and Atlanta Hawks said to be interested.

[112] On February 22, 2011, Anthony, along with point guard Chauncey Billups, was traded to the New York Knicks in a multi-player deal also involving the Minnesota Timberwolves.

On Easter Sunday, Anthony had arguably his best game in a Knicks uniform as he scored 43 points and hit two clutch three-pointers in a victory over Chicago.

[130] On April 7, 2013, Anthony scored 36 points and 12 rebounds, nine offensive, as the Knicks tallied their 12th straight win in a 125–120 victory over the Oklahoma City Thunder.

[152] For the 2013–14 season, Anthony averaged 27.4 points, 8.1 rebounds, and 3.1 assists in a league-leading 38.7 minutes per game, but would miss the NBA playoffs for the first time in his career.

[155] In just the team's third game in the season, Anthony became the 40th member of the 20,000 points club, when he hit a three-pointer early in the first quarter of a 96–93 victory over the Charlotte Hornets.

[159] On January 22, 2015, Anthony was named as a starter in the 2015 NBA All-Star Game, his seventh consecutive start and eight overall alongside LeBron James, Pau Gasol, Kyle Lowry and John Wall.

[160] After competing in the All-Star game and scoring 10 points, Anthony was ruled out for the rest of the season on February 18, after undergoing left knee surgery.

[166] On January 23, Anthony moved past Gary Payton as the league's 30th all-time career scoring leader in a 97–84 loss to the Charlotte Hornets.

[179] On March 12, 2017, in a 120–112 loss to Knicks cross-town rivals Brooklyn Nets, Anthony became only the third player to score 10,000 points for two franchises, joining Kareem Abdul-Jabbar (Milwaukee Bucks and L.A. Lakers) and Elvin Hayes (San Diego/Houston Rockets and Baltimore/Capital/Washington Bullets).

Morey said that Anthony "accepted every role" asked by D'Antoni, but that the "fit we envisioned when Carmelo chose to sign with the Rockets has not materialized; therefore we thought it was best to move on as any other outcome would have been unfair to him."

[239] On October 24, Anthony put up 28 points in a 121–118 win over the Memphis Grizzlies and moved past Moses Malone into the 9th place on the NBA all-time career scoring list.

In a disappointing season due to injuries and inconsistency, the Lakers finished with a 33–49 record (11th), and Anthony averaged 13.3 points per game with 37.5 percent three-point shooting in 69 appearances.

[245] After his rookie season, Anthony, along with fellow 2003 draftees LeBron James and Dwyane Wade, were chosen as members of the 2004 USA Olympic basketball team alongside veterans Allen Iverson, Stephon Marbury and Tim Duncan that won the bronze medal.

[254] In recognition of his performances and accomplishments in the tournament, Anthony was named co-USA Basketball Male Athlete of the Year (along with Kevin Durant) for the third time in his career.

[258] He also liked creating space from his defenders which allowed him to step into his jump shot or put the ball on the floor and drive to the basket and get to the free throw line.

[277] That same year, Anthony appeared in a video entitled Stop Snitchin', which warned that residents of Baltimore who collaborated with the police would face violence.

[292] In spring 2012, Anthony guest starred in several episodes of the Showtime series Nurse Jackie as a professional baseball player going through drug rehab.

[300] Despite the financial recession in Puerto Rico, Anthony saw this opportunity as a form of community outreach, as well as a long-term investment in a club that could ultimately be profitable.