[14][independent source needed] Her research has pushed the limits of electrospray ionization mass spectrometry, demonstrating that proteins and other complex macromolecules can be studied in the gas phase.

[16][17][18][19] Her research has made seminal contributions to gas-phase structural biology, with progress toward the study of protein complexes in their native environments for drug discovery.

[20] Additionally, she is a co-founder of OMass Therapeutics, a University of Oxford spin-out company applying mass spectrometry technology to drug discovery.

Most importantly, she has established that macromolecular complexes such as GroEL, ribosomes, and intact virus capsids can be generated in the gas phase and their electrospray mass spectra recorded.

[24][25] In 2011 she was given the Interdisciplinary Prize by the Royal Society of Chemistry for "development of a new area of research, gas-phase structural biology, using highly refined mass spectrometry techniques",[26] the Aston Medal, and the FEBS/EMBO Women in Science Award.

[30] In 2018 she won the Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry from the American Chemical Society.

[41] In 2024, she received the EPO European Inventor Lifetime Achievement Award for her work in mass spectrometry that significantly advanced biochemical research and medical diagnostics.