Invenizio was born in Voghera, the daughter of an official of the Kingdom of Sardinia.

[1] Invenizio made her writing debut in 1876, with the short story Un autore drammatico.

[1][2] Invernizio wrote about 150 novels and 20 collections of novelle, as well as four books of fiction for children.

[2] Influenced by feuilleton literature, she had an enormous popular following with her novels characterized by sensationalist, melodramatic and often gothic themes.

[1][2] She was often badly received by critics, and Antonio Gramsci referred to her as an "old trooper" and a "honest hen", eventually regretting these remarks.