Ducharme attended the Noble and Greenough School in Dedham, Massachusetts, and was ranked as the number 11 recruit in her class by ESPN.

However, when starting guard Paige Bueckers injured her left knee on December 5, Ducharme got more playing time as a result.

[2] Bueckers' and Azzi Fudd's injuries led to Ducharme assuming a scoring role, averaging 15.8 points over the next 15 games.

The return of the two players led to a decrease in Ducharme's role, as she had limited playing time during UConn's tournament run.

In the 2023 Big East tournament, Ducharme was removed from the Huskies' game against Georgetown with a head injury after colliding into her teammate, Aaliyah Edwards.