[1] Construction on the present building began around 1514,[2] predating the establishment of the diocese here in 1779 by over 250 years.
The church was designed by Baldassare Peruzzi under his patron Alberto III Pio, Prince of Carpi.
[3] With the creation of the diocese in 1779, the cathedral was assigned a Chapter, which was to consist of four dignities (the Archpriest, the Archdeacon, the Provost, and the Dean) and seventeen Canons.
It was granted the status of a minor basilica in 1979, on the occasion of the bicentenary of the establishment of the diocese.
After restoration work it was reopened for worship on 25 March 2017 with a solemn ceremony led by Cardinal Pietro Parolin.