The channel launched on 10 October 2010, coinciding with the opening of Turner Broadcasting System Europe's offices in Dubai Media City.

However, due to their direct relations with Turner, UAE Telecoms, Etisalat and Du continue to offer these channels to IPTV subscribers.

[4] Additionally, inVision in Saudi Arabia, Ooredoo in Qatar and Cablevision in Lebanon offer Cartoon Network and Boomerang as well.

On March 17, 2023, Twitter user Chahine Arfaoui posted a video of the channel getting hijacked and playing an unofficial animation of Roddy Ricch's Ballin.

Animation's Teen Titans Go!, Justice League Action, Rainbow's 44 Cats and Mattel WildBrain's Polly Pocket, My Little Pony: Friendship Is Magic etc.).

Cartoon Network Arabic has also offered numerous localized shows, such as Mansour and the Arabic version of Ben 10: Ultimate Challenge, which are the result of various partnerships deals with local production companies, including the Dubai-based Lammtara Pictures (Freej) or the Jordan-based Rubicon Group Holding (Ben & Izzy, Tareq wa Shireen).

[6] On Cartoon Network Arabic, Cartoonito was launched as a morning block broadcast every day starting from 4 September 2011.

However, the block was phased out on 1 April 2014, with some of its shows no longer available (although Baby Looney Tunes broadcasts on Boomerang HD and LazyTown airs on CN Arabic early in the morning).

On 6 February 2022, Cartoonito rebranded with the new 2021 logo and bumpers alongside its Turkish counterpart as part of the brand's Global re-introduction.

Cartoon Network Hindi provides children's animated programming to most South Asian expatriates in Arab World countries outside of India.