It is divided into five feeds, all originating from the Turner headquarters in Atlanta, Georgia, United States; four are in Spanish (Mexico/Dominican Republic, Argentina/Paraguay/Uruguay/Ecuador, Chile/Peru, Colombia/Panama/Venezuela/Central America), and the other is in Portuguese for Brazil.

[1] Cartoon Network began broadcasting in Latin America on April 30, 1993, Although much is not known about its first broadcast in the region, its beginnings were similar to its U.S. counterpart, whose programming focused solely on the classic cartoons of the Turner Entertainment film library, made up of studios Hanna-Barbera, MGM, Warner Bros. and Fleischer Studios.

and with this rebrand, Cartoon Network introduced new original series such as Foster's Home for Imaginary Friends, besides new acquisitions and programming blocks.

In April 2008, Cartoon Network presented its new locally produced content, a new campaign with a new image and a complete redesign of its websites.

[2] After these changes, the Adult Swim block was removed from the channel due to Jim Samples resigning in 2007 and the Programming Manager Cindy Kerr also leaving being succeeded by Pablo Zuccarino.

In June and August 2010, the channel began to use small idents with the logo in white and with the Toonix characters (similar to the Noods of the United States) originally promoting the 2010 Soccer World Cup.

[3] On July 13, 2011, the Toonix era began airing in the 16:9 aspect ratio (panoramic) with the series Total Drama Island although it was only experimental.

Several Turner channels joined in the celebration, including Warner, TruTV, I.Sat, Boomerang, TNT, TCM and Tooncast.

On August 11, 2014, the channel began the "Check It 3.0" era branding (known in Latin America as "Cartoon Network Renewed") and, also, it changed its aspect ratio from 4:3 to 16:9 in all its feeds.

Cartoon Network's HD feed was launched in Mexico on November 28, 2014, being Axtel the first cable operator to acquire the signal.

On August 3, new bumpers were shown depicting children imitating their favourite characters; this event was named a sub-rebrand of the Check it 3.0 era listed as 3.5.

10 of the 15 most popular shows among children aged 6-to-10 years old were broadcast by Cartoon Network Latin America,[citation needed] including The Powerpuff Girls, Dexter's Laboratory, Cow and Chicken, Johnny Bravo and I Am Weasel.

Cartoon Network Latin America has also aired original productions and live-action series such as La CQ and Use Sua Voz.

All five feeds are generated by central headquarters in Atlanta, Georgia and also broadcast both programming and continuity in English through SAP.

Toonami aired shows that were already on the lineup, these being Gundam Wing and Pokémon, and served as the home of Inuyasha and Dragon Ball GT.