The Augusto Delerme House (Spanish: Casa Augusto Delerme), also known as the Pablo Delerme House (Casa Pablo Delerme), is a historic 4-room Creole-vernacular residence located at 7 Benítez Guzmán Street in the town of Isabel Segunda, the largest settlement in the Puerto Rican island-municipality of Vieques.

The house was built in 1850 for a local prominent French-born landowner in the architectural style typical of French Creole dwellings in the West Indies with influence from the vernacular 19th-century Criollo architectural styles of Puerto Rico.

It was added to the National Register of Historic Places in 1994,[1] and on the Puerto Rico Register of Historic Sites and Zones in 2000.

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