[4] At the same time they also released music under the names of Siria, 3XM, Phalanx, Scarf!, Diamond and Akira, before ending these projects due to the success of Cascada.

Under Andorfine Records, they produced their debut and hit single, "Miracle", and its follow-up, "Bad Boy", in Germany.

[10] A total of seven singles were released from the album, four of which have been released in the United Kingdom: "Everytime We Touch", "Truly Madly Deeply" (originally by Savage Garden), "Miracle" and "A Neverending Dream" (originally by X-Perience), all of which gained Top 10 status apart from "A Neverending Dream" (which charted at No.46).

[11] The US saw the re-release of "Miracle" shortly after "Everytime We Touch"'s breakthrough, receiving high radio rotation and reaching the lower ends of the Billboard chart.

At the end of 2007, Cascada released their second album, Perfect Day in the UK and several Northern European countries,[17] followed by the remaining markets in the first quarter of 2008,[18] The album contained cover versions of Avril Lavigne's "Sk8er Boi", Pink's "Just Like A Pill", Patti Smith's "Because the Night" and the Jeffrey Steele song "What Hurts the Most", as well as two tracks, "Endless Summer" and "I Will Believe It", that were previously recorded by Horler and DJ Manian under the discontinued Siria name.

[26][27] In the United States, "Faded" and "Perfect Day" were released as singles, but received little airplay outside of the dance-radio circuit.

The song was released in the US in late September and peaked at 25, remaining in the chart for 17 weeks and making it the group's second Top 40 hit.

The album itself did not mirror the success of the single, yet it did chart in the Top 10 of many countries, including the UK where it went on to sell 100,000 copies.

"Dangerous" and "Fever" were follow-up singles released from the album, the former in the UK, and the latter in the US, Australia and the rest of Europe, neither experiencing success in terms of radio play, digital or physical sales.

Nevertheless, the group toured extensively to promote the album, even opening for Britney Spears during a stop in Germany.

A music video featuring Horler in full body paint of various colours in many scenes was released in November 2010 to promote the upcoming album.

On the weekend of 26 March 2011, Cascada shot two music videos for the upcoming singles "San Francisco" and "Au Revoir".

Both videos were directed by Lisa Mann and choreographed by Luther Brown, and both singles were featured on the album Original Me which was released on 20 June 2011 in the UK[28] and 29 November 2011 in the US.

After the release of the album, Horler posed for Playboy Deutschland in July 2011,[29] to mixed reactions from fans and critics.

[30][31] On 7 January 2012, Horler joined the jury of German singing contest Deutschland sucht den Superstar.

[32] On 16 March 2012, the music video for "Summer of Love" premiered in Germany,[33] followed by the compilation album Back on the Dancefloor.

In early June 2012, a video clip of Horler performing a cover of Corona's "The Rhythm of the Night" surfaced online.

[57] On 20 April 2017, Cascada released "Playground", the official song of the 2017 Ice Hockey World Championship held in Cologne, Germany and Paris, France.

In May 2021, Horler announced through an interview that "One Last Dance" would be released on 4 June 2021 and would be a collaboration with Canadian 1980s synth band Trans-X.

Collaborations with international DJs continue with: - "Never Let Me Go", in collaboration with Timmy Trumpet, ranked 10th in the Top 100 international DJs in 2021 according to DJ Magazine, and Harris & Ford, released on November 5, 2021 - The remix of "Never Be Lonely" by Jax Jones and Zoe Wees, released on March 8, 2024, which reached the top 10 in the UK charts and performed at the Capital FM Summertime Ball.

Confirming Cascada is now a solo project front by Natalie herself but was open to working with Manian again in the future.