In October 2020, Barrymore unofficially revived the character for a short video skit titled What if Casey Becker from Scream Lived?

[6] Barrymore was initially cast as lead character Sidney Prescott in Scream (eventually played by Neve Campbell), but opted to take the role of Casey instead to break the trope of high-profile actresses never dying in horror films.

[7] Barrymore stated: "In the horror film genre, my biggest pet peeve was that I always knew the main character was going to be slugging through at the end, but was going to creak by and make it.

After receiving a taunting and threatening phone call, she is ordered to answer horror film trivia questions to save the life of her 18-year-old boyfriend, football player Steve Orth (portrayed by actor Kevin Patrick Walls).

Since Barrymore was featured so heavily in promotional materials, the character being killed off was a "huge shocker that let the audience know that Scream was a film where all bets were off.

"[10] In his 2017 book Scream, author Steven West dissects the character, the way she acts in the film, and her appearance, writing "Drew Barrymore's previously exploited sex appeal... is deemphasized [with an] unbecoming bob wig..."[2] Writing for Comic Book Resources in January 2022, Renaldo Matadeen stated Casey was "Screams most iconic victim".

[12] Polygon ranked Casey as number 5 on their top 40 Scream characters list, behind Dewey Riley (4), Randy Meeks (3), Sidney Prescott (2), and Gale Weathers (1).