It stars Gael García Bernal, Roberta Colindrez, Perla De La Rosa, Joaquín Cosío, Raúl Castillo, El Hijo del Santo and Bad Bunny.

In the late 1980s, gay wrestler Saúl Armendáriz lives in El Paso, Texas with his mother, regularly crossing the border to Ciudad Juárez to participate in lucha libre wrestling matches.

[3][4] In July 2020, Gael García Bernal joined the cast of the film, with Roger Ross Williams set to direct from a screenplay he wrote alongside David Teague, with Amazon Studios in negotiations to distribute.

[16] David Rooney of The Hollywood Reporter called the film an "entertaining biopic, which doubles as a gorgeous depiction of mother-son love and an exhilarating exploration of fearless queer identity in a macho environment," adding, "Gael García Bernal nails his best role in years, giving a performance steeped in cheeky humor, resilience and radical self-belief.

"[3] Carlos Aguilar of Indiewire rated the film a B+, writing, "'Cassandro' balances the triumphant exaltation of Arbendáriz's singular evolution as a trailblazer who didn't set out to become one, with the obvious, still not entirely eliminated bigotry that made his trajectory so significant and groundbreaking in the first place.