Additionally, Colindrez is known for roles in the TV shows I Love Dick, Vida, and Amazon Prime's A League of Their Own, as well as the films Ms. White Light (2019) and Cassandro (2023).

Her main contributions to the film industry include portraying queer Latine characters and adapting them as her own to avoid stereotypes.

[5] The show closed in early 2014, and after a cameo in the Academy Award-winning film Birdman, Fun Home opened on Broadway in 2015, where it won five Tony Awards and was nominated for seven more.

[7] In 2018, Colindrez joined the cast of HBO's The Deuce about the life of sex workers in New York City in the 1970s to 1980s as the character Irene.

[13] Colindrez also originated the role of the farmer in a 2022 workshop of the first act of the Césaire José Carroll-Domínguez's epic historical play Spreckles which premiered in the 2022 Beyond The Box performance festival in Marfa, Texas with the group 'Marfa Live Arts' in the Crowley Theater.