Cassius McLean Shartel (April 27, 1860 – September 27, 1943) was a U.S. Representative from Missouri.

He attended the common schools and Kansas State Agricultural College at Manhattan.

He was admitted to the bar in 1881 and commenced practice in Sedan, Kansas.

He served as delegate to the Republican National Conventions in 1900 and 1936.

He served as president of the Missouri constitutional convention in 1922 and 1923.