Castelliri is a comune (municipality) of c. 3,500 inhabitants in the province of Frosinone in the Italian region Lazio, located in the valley of the Liri, about 90 kilometres (56 mi) southeast of Rome and about 20 kilometres (12 mi) northeast of Frosinone.

Castelliri borders the following municipalities: Arpino, Isola del Liri, Monte San Giovanni Campano, Sora.

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