[1] The origins of the castle are uncertain, though it was likely built by the d’Angiò family in the 12th century and associated with the monks of San Benedetto in Perillis, who held the small church of Santa Maria di Cartignano.

The castle was owned by the Cantelmo dukes of Popoli when they gained full control of the Bussi fief.

The subsequent history is uncertain until the second half of the 18th century when, after the fall of the feudal system, the current noble family owners, originating from the de Sanctis barons of Rocca Casale, acquired the main structure, except for the outer walls incorporated into the town.

In the 20th century, the castle was renowned in the region for being one of the richest and best-preserved, thanks to restoration and complete renovation by Orazio de Sanctis in the early part of the century, including the reconstruction of the partially ruined tower after previous structural tampering and destructive events culminating in the German military occupation during World War II.

The interior maintains its original rooms and chambers, furnished with period pieces, most of which were replenished in the early 20th century following the aforementioned destructive events.