Casto Creek is a stream in northwest Douglas County, Missouri.

[2] The headwaters of Casto Creek are north of Ava within one half mile of the Douglas - Wright county line.

The stream flows south roughly paralleling Missouri Route B then turns to the southwest west of the community of Mount Zion.

The stream continues to the southwest meeting its confluence with Cowskin Creek just north of Missouri Route 14 about three miles west of Ava.

This article related to a river in Missouri is a stub.