[2] This branch of the Medrano family in Soria were known as the Lords of San Gregorio, Almarza de Cameros, Cañaveruelas, Cabanillas, the Counts of Torrubia, etc.

The friars in Atienza lived in precarious conditions until the end of the 14th century, when the lady of the town, at that time Catalina de Lancaster, wife of King Enrique III of Trastamara, built a new conventual building at her own expense, and also undertook the construction of a new church, which, in any case, was left unfinished.

Demonstrating a commendable initiative to enhance the religious edifice of San Francisco in Atienza, Doña Catalina de Medrano, in 1507, instigated the construction of a main entrance, the restructuring of the choir, and numerous other intricate embellishments, marking a noteworthy chapter in the history of the friary.

Shortly before, in 1507, while Regent of Castile was Friar Francisco Ximénez de Cisneros, Catalina de Medrano's convent was declared a Royal Convent of Atienza, and its Guardian or Superior was appointed as Dean Regidor of the town, with two votes in the Councils, a designated person to replace him in the council position whenever he deemed it appropriate, and some other preeminences that demonstrated the high power that the friars had in the government of the high town of Atienza.

[2] Catalina's sister, Luisa de Medrano, was a renowned poet and philosopher and the first female professor at the University of Salamanca in Spain and Europe during the early 16th century.

[7] Her sister Luisa was educated alongside siblings of the royal family, and benefited from living in the climate of tolerance and advancement for women that Isabella I actively cultivated in her court, called by their contemporaries "puellae doctae" (learned girls).

When Garcí Bravo assumed responsibility for the Alcaidia of Atienza Castle, his relocation was not solitary; he brought his entire family, including his wife, children, and sons-in-law.

In the Castilian War of Succession, Catalina's maternal grandfather, Garci Bravo de Lagunas, played a pivotal role in securing the city of Sigüenza for Queen Doña Isabel.

Following the city's restoration to the Catholic Monarchs, Garci Bravo de Lagunas assumed the role of Alcaide, maintaining a prominent position in Sigüenza.

[8] In that year, during the siege of the city, he made a military testament in the royal style, which was later legally recorded on May 31, 1570, by Juan Sánchez Canales, a notary in Toledo.

[9] Catalina's father Don Diego López de Medrano and her maternal grandfather, Garcí Bravo, died in the Queen's service at the Siege of Málaga in 1487.

Juan Bravo's wife Catalina Núñez de Cienfuegos, on the occasion of the death of her husband and son-in-law in that action, received a heartfelt letter of condolences and gratitude from the Catholic Monarchs on June 7, 1487.