Catharina Buijs married (1732) the Amsterdam cartographer and publisher Johannes van Keulen II (1704–1755)[1] who owned a successful map-making business.
[2] After her husband's death, Catharina Buijs continued to run the Van Keulen family business which, according to Storms, made her "the most important female Dutch cartographer of the early modern period.
"[3] From the time she took charge of the business in 1755, Catharina Buijs was the official mapmaker for the Amsterdam office of the powerful Dutch East India Company.
[3] In addition, her company became a renowned publisher and seller of sea atlases and charts, helmsman's guides, and books, and also a manufacturer and distributor of navigation instruments.
[3] Beginning in 1772, she turned over partial control of the Van Keulen company to both of her sons, an arrangement that stood until her death in 1781.