Verplanck was born in February 1639 to New Netherland pioneers Abraham Isaacsen Verplanck and Maria de la Vigne.
Her siblings were Abigael Van Lear, Gulian, Isaac, Susanna, Jacomyntjie, Ariantje, Hillegondt, Isaac.
[3][4] Verplanck was married to newly arrived David Pieterse Schuyler in 1657 at the New Amsterdam Dutch Church.
[5] Their children included Myndert Schuyler, who was Mayor of Albany and David Davidse Schuyler who was a fur trader as well as a Mayor of Albany.
Her great-grandson Johannes Abeel was the father of the Seneca war chief Cornplanter.