The Cathedral of Our Lady of Guadalupe (Spanish: Catedral de Nuestra Señora de Guadalupe) is the main Roman Catholic church building of Canelones, Uruguay.

The first temple was built in 1775; around the small church, a township evolved.

In 1828, the priest Juan Francisco Larrobla blessed here the first Flag of Uruguay.

[3] In 1945, Cardinal Antonio Barbieri elevated the church to National Sanctuary of the Virgin of Guadalupe.

This article about a Roman Catholic cathedral in Uruguay is a stub.