Cecina (Italian pronunciation: [ˈtʃɛːtʃina]) is a comune (municipality) of 28,322 inhabitants in the Province of Livorno in the Italian region Tuscany, located about 80 kilometres (50 mi) southwest of Florence and about 30 kilometres (19 mi) southeast of Livorno.

An archaeological park close to the town houses the remains of a Roman villa from the 1st century BC.

A settlement was founded here by the Roman consul Albinus Caecina, who was a descendant of an ancient Etruscan family.

After the fall of the Western Roman Empire, the territory suffered a long period of decline, which only came to an end when the Grand Duke Leopold II of Tuscany began to develop local agriculture.

The modern town was founded in 1852, but a part of the city was destroyed during World War II.