Each week, the show featured four celebrities, on a pair of AMF or Brunswick lanes installed inside KTTV's studios, pitted against each other in teams of two.

The weekly series was a by-product of The Celebrity Bowling Classic, a 90-minute TV special produced in 1969 for the Metromedia-owned stations, benefitting the Joseph P. Kennedy Jr. Foundation.

In 2008, TVS Television Network began producing Celebrity Bowling for TV syndication, using the AMF Lanes at the Silver Nugget Casino in North Las Vegas, Nevada.

The format was similar to the original, with an added twist that an audience member contestant could be called to bowl in place of a celebrity.

Episodes have aired on Decades, ESPN Classic, the Retro Television Network, My Family TV, and on the Roku device on the N2TV channel.

[4] Selected episodes aired on Decades (a joint venture between Weigel and CBS) March 8–10, 2015, and as part of special "binge" weekends on October 3–4, 2015, and May 28–29, 2016.

Jed Allan remarked that the previous high score was a 206, which was reached by Greg Morris and John Beradino in Episode 10.

The lowest score recorded during the original series is presumed to be a 66 by the team of Charles Nelson Reilly and Robert Clary in Episode 142.

Reference is made at the show close by Jed Allan to the pair having "beaten" the long-standing record of 67 which was bowled by two of the Lennon Sisters.