[2] The experimentally determined composition of cellulin is 39% glucan (composed of beta-1,3- and beta-1,6-linked glucose units) and 60% chitin.
At specific concentration of β-cellulin at 0.2, 2 and 20 ng/mL rapid repair was induced to corneal epithelial stem cells.
During these concentrations β-cellulin promotes phosphorylation of erk1/2 signaling pathway in mice during cornea repair.
To confirm this, the mutation of erk1/2 inhibited this pathway and slowed the repair of cornea cells in mice.
[5] Despite being produced in large quantities by pancreatic islet cells, β-cellulin, an epidermal growth factor, appears to have little relevance in regulating insulin production.