According to the 2000 federal census data, Central Greene School District served a resident population of 16,681.

The facilities include a pool, a football stadium, an auditorium, a soccer field and indoor basketball courts that are used as a community center for the Waynesburg area.

High school students may choose to attend Greene County Career and Technology Center for training in the construction and mechanical trades.

Central Greene School District offers a variety of clubs, activities and interscholastic sports.

According to PIAA directory July 2012 [4] On August 9, 2011, the Central Greene School Board voted[5] to close Perry Elementary as a cost-saving measure.