The Central Post Office (Ukrainian: Дніпровський головпоштамт, romanized: Dniprovskyi holovposhtamt) is a 20th-century building that formerly houses the Ukrposhta for the city of Dnipro, Ukraine.

[3] Long before the present building was built, around the end of the 18th century, the history of the post office in Ekaterinoslav started.

Mikhail Vlasov, a merchant, took over the upkeep of the post station with four horses on 1 October 1797, at a fee of 300 rubles annually.

[3] The building on 62 Karl Marx Avenue, where a house owned by nobleman Anton Schekutin formerly stood, is now home to the General Post Office of Dnipropetrovs'k.

Under the supervision of city architect Alexander Miklashevs'ky, engineers Panafutin and Sokolovych extensively altered the building's base.

The main post and telegraph office were to be situated in the existing building, but a new one was built next to it in accordance with the plans of Saint Petersburg architect Vasyl Bocharov.

[2] After visiting Ekaterinoslav in September 1905, senior architect Nikonov of the Main Directorate of Posts and Telegraphs sent a report to Saint Petersburg stating that the work was done.

[4] The 1917 Russian Revolution left its impact on the building, as did a protracted conflict between Red Guards and Haydamak forces who had taken control of this structure.