Centre High School is a rural public secondary school located 5 miles south of Lost Springs and 2 miles north of Lincolnville along U.S. Highway 77 in Marion County, Kansas.

It is operated by Centre USD 397 school district.

It is the sole public high school for the communities of Lincolnville, Lost Springs, Pilsen, Tampa, Ramona, Antelope, Burdick, and nearby rural areas of Marion / Morris / Dickinson / Chase Counties.

High schools from Lincolnville, Lost Springs, Pilsen, Burdick, Tampa and Ramona consolidated into Centre Rural High School.

Other notable details include: The high school is a member of T.E.E.N., a shared video teaching network, started in 1993, between five area high schools.