Centromochlus perugiae is a species of benthopelagic fish, a member of the Auchenipteridae (driftwood catfish) family.

Honeycomb catfish are under 3 inches (76 mm) fully grown.

Honeycomb catfish like to anchor themselves into crevices in driftwood and hide.

They are mostly nocturnal and seek hiding spaces and shade.

A very peaceful species, in an aquarium, honeycomb catfish do not bother other inhabitants of a community tank.